The micro-organisms present in the gastro-intestinal tract, known collectively as gut microbiota, have been recognised to provide essential functions for host physiology, including metabolism, immunity and neuronal development.
Diet is considered to be a key component affecting the development of gut microbiota from infancy and throughout the life cycle. Macronutrients, probiotics, fibres, polyphenols and prebiotics are strong drivers shaping the composition of the gut microbiota. Modulating gut microbiota composition and function through diet may result in either beneficial or detrimental consequences for host health.
To understand the potential effect of diet on complex human microbiomes, improvements are needed in research in the field in terms of technical capabilities. Yet data from large cohorts are not always clear-cut or comparable. Personalised nutrition is an emerging data-driven approach, potentially enabling diets tailored to the individual in various clinical contexts.
Understanding how individuals respond to a specific dietary intervention would contribute to a knowledge base for future investigations into personalised nutrition. With the ongoing projects we aim to address the gaps in scientific knowledge concerning prebiotics, probiotics and dietary intervention on human health.
NUTRITION TASK FORCES JOINED FORCES TO UNDERSTAND WHERE WE STAND TODAY REGARDING THE MECHANISMS UNDERLINING THE GUT-BRAIN AXIS
A workshop organised in December 2019 brought together key experts from different fields of expertise to debate and discuss on the current knowledge and data gaps on the gut-brain axis.